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Research Snapshot: Treatment and survival trends in patients with early laryngeal cancer

Stephanie Misono, M.D. M.P.H., and colleagues within the University of Minnesota School of Public Health and School of Medicine recently released the results of a study examining trends in treatment of people within the early stages of laryngeal cancer.

The objectives of this study were

  • To identify factors associated with treatment differences.
  • Characterize changes in treatment patterns over time.
  • Compare survival rates across treatment types in patients who received treatment.

Using a cancer surveillance database, researchers analyzed rates and trends in patients who were treated from 1995 to 2009. 10,429 adult patients diagnosed with early cancer of the larynx (voicebox) were studied…

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In the News: U of M offers new cancer treatment for neuroblastoma

Neuroblastoma, a type of childhood cancer, is difficult to treat. And according to the American Cancer Institute, about 700 people in the United States are diagnosed with this form of cancer each year.

Raymond Yeager has dealt with the neuroblastoma since he was 14 years old. Now 20, he’s undergone many treatments including chemotherapy, radiation therapy, surgery, a stem cell transplant and immunotherapy. Unfortunately, nothing has helped…

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For dogs, sole gene doesn’t equate to cancer

If you’re a dog lover, we have some good news. It turns out that a better understanding of the mechanisms behind aging and cancer could reduce the number of canines over the age of 10 that die from cancer each year. A better understanding of those same mechanisms may even yield big news for humans down the road.

Recently, University of Minnesota researchers made a surprising discovery about one gene implicated in canine aging. Their finding centered around a gene known as “TERT.”

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In the News: Western scientists look to traditional Chinese medicine to treat cancer

Traditional Chinese plants and medicines might seem like an unusual way to treat a serious illness. However, these historic remedies have caught the eye of medical researchers. The latest research from Samuel Waxman, M.D., of Mount Sinai Hospital states that traditional Chinese medicine could be as advantageous to chemotherapy in the treatment of some forms of cancer including leukemia.

Arsenic trioxide, traditionally used in Chinese medicine, was approved as a treatment for leukemia in 2000 by the U.S. Food and Drug Administration. Following this approval, research later proved that patients that were given chemotherapy followed by arsenic trioxide did better than the patients that received the standard chemotherapy alone.

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Health department: Minnesota high school girls continue to tan indoors despite warnings

According to the Minnesota Department of Health, a significant number of high school girls are still tanning indoors despite skin cancer warnings.

The results of the Minnesota Student Survey revealed that 34 percent of white 11th grade females tanned indoors last year with more than half reporting they did so ten or more times. This is the first time the survey, which collects data from middle schools and high schools statewide, has addressed indoor tanning.

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Collaborative research opens door for improved osteosarcoma treatment

About thirteen years ago, Jamie Modiano, V.M.D, Ph.D., from the University of Minnesota’s College of Veterinary Medicine, began a collaborative research process with members of the Broad Institute, Ohio State University, and North Carolina State University. The goal of the group: to understand more about Osteosarcoma (bone cancer) and how it is similar between canines and humans.

Osteosarcoma is a rare disease in humans most commonly found in children. The condition is far more common in dogs, however. According to Modiano, there are about 10,000 bone cancer cases in dogs annually compared to less than 1,000 in humans.

“While the disease impacts more dogs than humans, the clinical behavior of the disease is very similar,” Modiano said.

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