Ling Li is taking Alzheimer’s disease research in a new direction.
Recently, Scientific American took a minute to feature her preliminary research into a novel approach to Alzheimer’s drug development.
The advancement of medicine and technology have allowed doctors to find many uses for medications beyond the initially intended benefits. For example, a teenager’s alopecia was recently cured by an arthritis drug. This type of use is called “off-label drug use,” the common term for using a medication to treat or manage symptoms outside the approved uses.
Off-label drug use is more prominent than you may think. For example, aspirin helps reduce blood pressure and oral contraception can be used to treat acne or endometriosis. These are all examples of using a drug off-label.
A new compound in development at the University of Minnesota shows promise as a breakthrough drug for treating chronic pain.
The new compound, developed by Philip Portoghese, Ph.D., of the University of Minnesota’s College of Pharmacy, appears to be the first of its kind. A patent has been applied for, and the University’s Center for Translational Medicine has been conducting proof-of-concept studies. As a potential medication, the compound offers benefits lacked by current medications: It does not induce the body to develop tolerance or dependence, as opioid painkillers do. It is more potent than other opioid pain medications. It reduces and inhibits neuropathic pain, post-operative pain, burn pain, spinal injury pain and inflammation.
Tylenol should relieve pain, cough suppressants should ease cough and serious ailments should reliably respond to vital medication. But when a prescribed medicine doesn’t do its intended job, it can be difficult to decide who or what is to blame.
It doesn’t help that sometimes the problem doesn’t lie within the medicine or the doctor; it can lie within your genes.
Every day, more than 1,500 amazing men and women help grow the health sciences programs at the University of Minnesota. These are the faculty of the six schools and colleges that make up the Academic Health Center (AHC), and each has a story to tell.
Through a new video series titled “Every Day,” the AHC is taking viewers inside the lives of our faculty. Just like middle school teachers with a life outside the classroom, our researchers and physicians live exciting lives outside their daily work at the university. Rather than simply profiling their research or clinical specialties, we focus instead on what drives them to make the world a better place.
In this video series, our experts leave their office walls behind and welcome viewers into their personal lives. We encourage you to watch how these researchers better themselves and the world we share together, every day.
Watch the videos here
Editor’s note: Ashley Artmann is a doctor of pharmacy student at the University of Minnesota College of Pharmacy. To document her five-week rotation in Germany, Artmann is blogging about her experiences learning about German pharmacy education and practice. Find this and additional posts from Artmann at aeartma.blogspot.com.
Last Tuesday we ventured via bus and train in the rain to Düsseldorf to visit their university and pharmacy school.