Academic Health Center
Stay Connected
in-the-news

Promising research for a new antibiotic

A recent study in Nature identifying a potential new antibiotic garnered a lot of attention in the media and research community. Besides identifying a new antibiotic, the study used a method that has the potential to unlock significantly more antibiotics.

Health Talk spoke about the study with Courtney Aldrich, Ph.D., associate professor of medicinal chemistry in the College of Pharmacy and editor-in-chief of ACS Infectious Diseases, the first chemical-based journal on infectious diseases.

Read more
in-the-news

In the News: Generic drug prices soar

High-priced prescription drugs are not unfamiliar to the American consumer.

But generic drugs – widely accepted as the cheaper alternative to big brand names – are making their own name in high pricing as of late.

Generic drug prices on some commonly prescribed medications have risen by as much as 500 percent over the past year.

University of Minnesota College of Pharmacy pharmaceutical economist Stephen Schondelmeyer, Pharm.D., Ph.D., spoke with WCCO Radio’s Chad Hartmann about the rising cost trend and what it could mean for consumers.

Read more
expert-perspectives

The Expert Is In: Liver damage from dietary supplements

Liver damage is a well-established risk of many prescription drugs. However, recent research out of the Einstein Medical Center in Philadelphia reveals herbal and dietary supplements may be causing liver damage in some U.S. regions as well. Bodybuilding and non-bodybuilding herbal supplements alike were implicated in the find, which spotlighted a small slice of one of the world’s fastest growing industries.

The findings came as no surprise to Chengguo Xing, Ph.D., professor of medicinal chemistry at the University of Minnesota College of Pharmacy and member of the Masonic Cancer Center, University of Minnesota.

Xing is investigating how to reduce liver damage associated with a kava dietary supplement, which was found earlier this year to prevent tobacco-smoke induced lung cancer in a mouse model.

Here’s what Xing had to say:

Read more
in-the-news

In the News: A new idea for treating Alzheimer’s

Ling Li is taking Alzheimer’s disease research in a new direction.

Recently, Scientific American took a minute to feature her preliminary research into a novel approach to Alzheimer’s drug development.

Read more
patient-care

Some drugs may be off-label, but not off focus

The advancement of medicine and technology have allowed doctors to find many uses for medications beyond the initially intended benefits. For example, a teenager’s alopecia was recently cured by an arthritis drug. This type of use is called “off-label drug use,” the common term for using a medication to treat or manage symptoms outside the approved uses.

Off-label drug use is more prominent than you may think. For example, aspirin helps reduce blood pressure and oral contraception can be used to treat acne or endometriosis. These are all examples of using a drug off-label.

Read more
research-and-clinical-trials

New compound shows promise in treating chronic pain

A new compound in development at the University of Minnesota shows promise as a breakthrough drug for treating chronic pain.

The new compound, developed by Philip Portoghese, Ph.D., of the University of Minnesota’s College of Pharmacy, appears to be the first of its kind. A patent has been applied for, and the University’s Center for Translational Medicine has been conducting proof-of-concept studies. As a potential medication, the compound offers benefits lacked by current medications: It does not induce the body to develop tolerance or dependence, as opioid painkillers do. It is more potent than other opioid pain medications. It reduces and inhibits neuropathic pain, post-operative pain, burn pain, spinal injury pain and inflammation.

Read more