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Master regulator of key cancer gene found, offers new drug target

Gene partnership may be fueling cancer spread in as much as 20 percent of cancers

A key cancer-causing gene, responsible for up to 20 percent of cancers, may have a weak spot in its armor, according to new research from the Masonic Cancer Center, University of Minnesota.

The partnership of MYC, a gene long linked to cancer, and a non-coding RNA, PVT1, could be the key to understanding how MYC fuels cancer cells. The research is published in the latest issue of the journal Nature.

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U of M health sciences researchers achieve greatness every day

Every day, more than 1,500 amazing men and women help grow the health sciences programs at the University of Minnesota. These are the faculty of the six schools and colleges that make up the Academic Health Center (AHC), and each has a story to tell.

Through a new video series titled “Every Day,” the AHC is taking viewers inside the lives of our faculty. Just like middle school teachers with a life outside the classroom, our researchers and physicians live exciting lives outside their daily work at the university. Rather than simply profiling their research or clinical specialties, we focus instead on what drives them to make the world a better place.

In this video series, our experts leave their office walls behind and welcome viewers into their personal lives. We encourage you to watch how these researchers better themselves and the world we share together, every day.

Watch the videos here

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In The News: From research to reality

Taking research from the test tube and turning it into treatment for people in need can take a lot of time.

“Making the leap from basic science to a treatment is formidable. The failure rate exceeds 95 percent,” Jeffrey Miller, M.D., and Timothy Schacker, M.D.Medical School wrote in a recent edition of Minnesota Health Care News.

But the degree of success could go up with a newer way of approaching studies, called translational research. The method aims to take discoveries and turn them into practical solutions that can improve the health of people.

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U of M study reveals rats show regret, a cognitive behavior once thought to be uniquely human

New research from the Department of Neuroscience at the University of Minnesota reveals that rats show regret, a cognitive behavior once thought to be uniquely and fundamentally human.

Research findings were recently published in Nature Neuroscience.

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Shlafer turns advocacy for incarcerated pregnant women into legislation

Rebecca Shlafer, Ph.D.Department of Pediatrics, has been busy lately. After assisting with Isis Rising to help incarcerated mothers at Shakopee Women’s Prison, the Assistant Professor was part of Sesame Street’s Little Children, Big Challenges: Incarceration project. The initiative supports young children who have an incarcerated parent with interactive resources.

While Shlafer has been educating others about the issues surrounding incarcerated parents, last month she saw her advocacy turn into legislation. Governor Mark Dayton signed a bill that will help address the needs of incarcerated women around the periods of pregnancy and childbirth.

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U of M study: Reduction in neurosurgical resident hours appears to have no significant positive effect on patient outcomes

A reduction in neurosurgeon resident duty hours appears to result in no significant changes in patient outcomes, according to new research from the Department of Neurosurgery at the University of Minnesota. The reduction in resident duty hours was mandated in 2003 by the Accreditation Council for Graduate Medical Education (ACGME) when it imposed a mandatory maximum 80-hour work-week restriction on medical residents. Prior to this mandate, residents often worked in excess of 100 hours per week.

Findings were published today in the Journal of Neurosurgery.

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