A new University of Minnesota-led study of osteoporosis in men recently published in the British Medical Journal found the proportion of older men labeled as abnormal and warranting drug treatment ranged from 2 percent to 25 percent depending on the definition of osteoporosis and absolute fracture risk intervention thresholds applied to the population.
Older men experience 29 percent of all bone fractures among United States adults 50 years of age or older. However, the best strategy to identify men who are candidates for drug treatment is not yet known. The uncertainty exists, in part, because osteoporosis is not as well defined for men as it is for women. In addition, drug treatment in women with osteoporosis reduces risk of bone fractures, but the effect of treatment on fracture risk has not been evaluated in men.