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expert-perspectives

Almost two decades later, doctor reflects on using embryo selection to save young girl’s life

Molly Nash was not expected to live to the age of 10. But her parents, and John Wagner, M.D., professor with the Department of Pediatrics in the Medical School, refused to let the genetics of her disease have the final word.

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research-and-clinical-trials

ICU Patients Can Safely Administer Their Own Sedatives, New Study Finds

Patients in intensive care units (ICUs) are often sedated to enhance their comfort with mechanical ventilator breaths and reduce anxiety. However, the prescribed sedatives are based on clinicians’ assessments of their patients’ discomfort or anxiety and may not meet their needs. Now, researchers at the University of Minnesota have found that patients can self-administer their own sedative in some cases, which could lead to a more tailored and possibly effective care experience.

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research-and-clinical-trials

New Study Determines What Makes ‘Successful’ Smile

New research shows that less is more when it comes to a successful smile, which could have implications for how surgeons and therapists work with patients who have facial paralysis. The University of Minnesota research may be critically important for helping stroke patients and other people with facial paralysis improve quality of life.

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research-and-clinical-trials

Research Snapshot: A detailed look at HTLV-1, the retrovirus that causes T-cell Leukemia

It is generally believed that virus particles need to be fully formed to transmit a virus. But a recent study by researchers in the Academic Health Center’s Institute for Molecular Virology (IMV) shows this may not be the case.

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expert-perspectives

Fighting hydrocephalus

“Here at the University of Minnesota, hydrocephalus is the most common condition we treat in pediatric neurosurgery,” explained Daniel Guillaume, M.D., M.S., associate professor in the Department of Neurosurgery at the University of Minnesota Medical School, “and as such we are constantly searching for better treatments.”

Hydrocephalus is a serious condition with many causes, which in some cases are not fully understood. The primary characteristic is the buildup of too much cerebrospinal fluid (CSF) in the brain and spinal cord. That causes potentially harmful pressure on brain tissue. Without treatment, the outcome can result in severe disability and even death.

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expert-perspectives

Man flu or myth? Why we study mice of different genders to understand illness

The term man flu is typically used in jest; perhaps in conversation between two women joking about how their husbands react to illness. For others, the phrase may be completely new. However, recently it has risen to the surface enough in mainstream media and water cooler discussions to draw interest from researchers.

Researchers at the University of Ottawa recently set out to essentially answer the question, do identical infections actually make males more miserable than females? The study involved injecting lab mice with molecules from bacteria. They found at the onset of infection the male mice’s body temperature fell more than females’ did. An article in Stat extrapolated this fit with the idea of the man flu.

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